A
5200 Harry Hines Blvd.
,
Dallas
,
TX
75235
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General Information
Alias: Depakene
Performed: Sun-Sat
Turn Around Time: 2-4 days
CPT Codes: 80164, 80165
Performed By: Referral Lab
Clinical Utility: Free valproic acid may be important to monitor in patients with altered or unpredictable protein binding capacity because valproic acid exhibits variable, dose-dependent protein binding. Valproic acid is also subject to drug-drug interactions due to displacement of protein binding. Calculating percent free attempts to minimize differences in test cross-reactivity and may be useful in dose optimization. Adverse effects may include headache, somnolence and dizziness.
Link:
Valproic Acid, Free and Total
Components
| Name |
Method |
Sex |
Age Range |
Ref. Range Low |
Ref. Range High |
Units |
| Valproic Acid, Free |
Quantitative Enzyme Multiplied Immunoassay Technique |
|
|
Therapeutic Range: 7-23 |
Toxic: Greater than 30 |
ug/mL |
| Valproic Acid, Total |
Quantitative Enzyme Multiplied Immunoassay Technique |
|
|
Therapeutic Range: 50-125 |
Toxic: Greater than 150 |
ug/mL |
| Valproic Acid, Percent Free |
|
|
|
5-18 |
|
% |
Specimen Requirements
| Type |
Container |
Volume |
Units |
Collection / Delivery |
Storage / Transport |
Off Campus |
| Blood |
Red no Gel, 6mL |
|
|
Deliver within 2 hours of collection. |
Room Temperature |
Transport serum specimen refrigerated. |