STRIATED MUSCLE ANTIBODIES, IGG

General Information

Alias: CMA

Performed: Mon-Sat

Turn Around Time: 2-4 days

CPT Codes: 86255. if reflexed add 86256

Performed By: Referral Lab

Notes: If positive, results are titered.

Clinical Utility: When detected in the presence of acetylcholine receptor (AChR) antibody, striated muscle antibodies, which bind in a cross-striational pattern to skeletal and heart muscle tissue sections, are associated with late-onset myasthenia gravis (MG). Striated muscle antibodies recognize epitopes on three major muscle proteins, including: titin, ryanodine receptor (RyR) and Kv1.4 (an alpha subunit of voltage-gated potassium channel [VGKC]). Isolated cases of striated muscle antibodies may be seen in patients with certain autoimmune diseases, rheumatic fever, myocardial infarction, and following some cardiotomy procedures.

Link: Striated Muscle Antibodies, IgG with Reflex to Titer

Components

Specimen Requirements