A
5200 Harry Hines Blvd.
,
Dallas
,
TX
75235
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General Information
Alias: Rapamune, Rapamycin
Performed: Sun-Sat
Turn Around Time: 1-2 days
CPT Codes: 80195
Performed By: Referral Lab
Notes: Therapeutic ranges applies to trough specimen drawn immediately prior to a.m. dose. A range of 12-20 ng/mL has been suggested for liver transplant. The optimal therapeutic range for a given patient may differ from this suggested range based on the indication for therapy, treatment phase (initiation or maintenance), use in combination with other drugs, time of specimen collection relative to prior dose, type of transplanted organ, and/or the therapeutic approach of the transplant center.
Clinical Utility: Optimize drug therapy and monitor patient adherence.
Link:
Sirolimus by Tandem Mass Spectrometry
Components
| Name |
Method |
Sex |
Age Range |
Ref. Range Low |
Ref. Range High |
Units |
| Sirolimus, BLD |
HPLC-MS/MS |
|
|
Kidney transplant (in combination with Cyclosporine): 4-12 |
Toxic value: > 25 |
ng/mL |
Specimen Requirements
| Type |
Container |
Volume |
Units |
Collection / Delivery |
Storage / Transport |
Off Campus |
| Whole Blood |
Lavender EDTA(K2), 4mL |
|
|
1. Draw blood immediately before a scheduled dose. 2. Send specimen in original tube. |
Room Temperature |
Refrigerated Lavender top (EDTA) |