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General Information
Alias: RPN1/MECOM (EVI1), EGR1, D7S486, RUNX1T1/RUNX1, KMT2A (MLL), CBFB, PML/RARa
Performed: Sun-Sat
Turn Around Time: 3-10 days
CPT Codes: 88271 x6; 88275 x6; 88291
Performed By: Referral Lab
Notes: This FISH panel includes RPN1/MECOM (EVI1), EGR1, D7S486, RUNX1T1/RUNX1, KMT2A (MLL), and CBFB. The probe for PML/RARα is added automatically and is performed along with the panel. However, due to the longer turnaround time required for the panel, the result of this probe is reported separately, as soon as results are available.
Clinical Utility: Identify prognostically important abnormalities in newly diagnosed AML. Monitor response to therapy or progression of disease with probe panel.
Link:
Acute Myeloid Leukemia (AML) Panel by FISH
Components
Name |
Method |
Sex |
Age Range |
Ref. Range Low |
Ref. Range High |
Units |
Acute Myeloid Leukemia (AML) Panel by FISH |
Fluorescence in situ Hybridization |
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ZR PML/RARA by FISH |
Fluorescence in situ Hybridization |
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Specimen Requirements
Type |
Container |
Volume |
Units |
Collection / Delivery |
Storage / Transport |
Off Campus |
Whole Blood |
4mL Grn Na Hep |
|
|
|
Room Temperature |
|
Bone Marrow |
Syringe |
|
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Room Temperature |
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